Human trophoblast neoplasms
- 505 Pages
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Plenum Press , New York
Trophoblastic tumors -- Congresses., Trophoblastic tumors -- Chemotherapy -- Congresses., Trophoblastic Tumor -- congresses., Uterine Neoplasms -- congre
|Statement||edited by Roland A. Pattillo and Robert O. Hussa.|
|Series||Advances in experimental medicine and biology ;, v. 176|
|Contributions||Pattillo, Roland A., Hussa, Robert O.|
|LC Classifications||RC280.P6 W67 1982|
|The Physical Object|
|Pagination||x, 505 p. :|
|LC Control Number||84011367|
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This book addresses neoplasms of the human trophoblast. The scant literature available on the epidemiology of trophoblast neoplasms suggests that they are as much as ten times more common in Africa, Asia, India, and much of the developing world than in Western countries.
The stimulus for the. This book addresses neoplasms of the human trophoblast. The scant literature available on the epidemiology of trophoblast neoplasms suggests that they are as much as ten times more common in Africa, Asia, India, and much of the developing world than in Western countries.
The stimulus for the book. This book addresses neoplasms of the human Human trophoblast neoplasms book. The scant literature available on the epidemiology of trophoblast neoplasms suggests that they are as much as ten times more common in Africa, Asia, India, and much of the developing world than in Western countries.
This book addresses neoplasm of the human trophoblast. The scant literature available on the epidemiology of trophoblast neoplasms suggests that they are as much as ten times more common in Africa, Asia, India, and much of the developing world than in Western countries.
The implantation process involves complex and synchronized molecular and cellular events between the uterus and the implanting embryo. These events are regulated by paracrine and autocrine factors.
Trophoblast invasion and migration through the uterine wall is mediated by molecular and cellular interactions, controlled by the trophoblast and the maternal. From Trophoblasts to Human Placenta Harvey Kliman Sunday, Octo Page 2 of 19 junctional trophoblast the specialized trophoblast that keep the placenta and external membranes attached to the uterus.
spiral arteries the maternal arteries that travel through the myo– and endometrium which deliver blood to the placenta. Human trophoblast function during implantation process Article Literature Review (PDF Available) in Reproductive Biology and Endocrinology.
Cite this chapter as: Berkowitz R.S. et al. () First World Congress on Trophoblast Neoplasms. In: Pattillo R.A., Hussa R.O. (eds) Human Trophoblast : R. Berkowitz, S. Lahey, G. Steele, A. Rayner, M. Rodrick, D. Goldstein, R. Harahap, R. The trophoblast cell lines have been removed from their in vivo environment for many passages and some of their properties may be distorted.
Regardless, they are commonly used as a convenient and valuable resource to provide insight into trophoblast function.
A list of commonly used human trophoblast cell lines is provided in Table Book review in this article: Human Trophoblast Neoplasms—Advances in Experimental Medicine and Biology.
Vol. by K. Pattillo & R. Hussa. The trophoblast model of cancer can be stated as a set of 11 core predictions and 3 adjunctive or nonessential components. The trophoblast model of cancer is a detailed, testable model that should be investigated within an overlapping set of fields including oncology, histology, physiology, molecular biology, and by: 6.
Clinical significance. The invasion of a specific type of trophoblast (extravillous trophoblast) into the maternal uterus is a vital stage in the establishment of e of the trophoblast to invade sufficiently is important in the development of some cases of firm of an attachment may lead to placenta accreta.
Gestational trophoblastic disease is a pregnancy Gives rise to: caul. Trophoblast cells are specialized cells in the placenta that mediate the interactions between the fetus and mother.
Details Human trophoblast neoplasms FB2
Okae et al. report the derivation of human trophoblast stem cells from blastocysts and early placentas, which will provide a powerful tool to study human placental development and by: Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption Lucas Sagrillo-Fagundes * 1, Hélène Clabault * 1, Laetitia Laurent * 1, Andrée-Anne Hudon-Thibeault 1, Eugênia Maria Assunção Salustiano 1, Marlène Fortier 1, Josianne Bienvenue-Pariseault 1 Cited by: Trophoblast Markers.
Trophoblasts (from Greek threphein: to feed) are cells forming the outer layer of a blastocyst which provides nutrients to the embryo and develop into a large part of the are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg.
() This treatment regimen is based on the Trophoblastic Theory of cancer. This theory was originally proposed by a Scottish embryologist named John Beard (), and was resurrected by William Donald Kelley, DDS ().() Above Left Image: Placenta anatomic diagram from Gray’s Anatomy published in Transduction of human trophoblast cells by recombinant adenoviruses is differentiation dependent.
MacCalman CD(1), Furth EE, Omigbodun A, Kozarsky KF, Coutifaris C, Strauss JF 3rd. Author information: (1)Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphiaby: The human placenta has been dubbed the “least understood organ” ; unfortunately, this statement also applies to the stem cells which contribute to this organ, namely, trophoblast stem cells (TSCs) which give rise to the epithelial components of the dge of the TSC niche in the polar trophectoderm of the mouse embryo led to their successful derivation almost 20 Cited by: 9.
Human embryonic stem (ES) cells have the potential to form any cell type, but ironically, the first cell lineage to form during development still represents a surprising challenge.
The first cell type to become specialized is an epithelial cell that later defines the boundary between the embryo and mother for the formation of the placenta. Other articles where Trophoblast is discussed: blastocyst: now referred to as the trophoblast.
It does not contribute directly to the formation of the embryo but rather serves to establish a connection with the maternal uterus. It is a precursor of the placenta. Pathology of the Human Placenta remains the most comprehensive and authoritative text in the field.
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It provides extensive information on the normal placenta, encompassing physiology, metabolism, and endocrinology, and covers the full range of placental diseases in great detail. Further chapters are devoted to abortions, molar pregnancies, Reviews: 1. The trophoblast, i.e.
the peripheral part of the human conceptus, exerts a crucial role in implantation and placentation. Both processes properly occur as a consequence of an intimate dialogue between fetal and maternal tissues, fulfilled by membrane ligands and receptors, as well as by hormone and local factor release.
During blastocyst implantation, Cited by: Shih IM, Kurman RJ. The pathology of intermediate trophoblastic tumors and tumor-like lesions. Int J Gynecol Pathol,An intermediate trophoblast is a distinctive trophoblastic cell population from which four trophoblastic lesions are thought to arise: exaggerated placental site (EPS), placental site nodule (PSN), placental site trophoblastic tumor (PSTT), and epithelioid.
A collection of cutting-edge laboratory techniques for the study of trophoblast and placental biology. The techniques presented range from experimental animal models, to animal and human placental organ and cell culture systems, to morphological, biochemical, and molecular strategies for assessing trophoblast/placental growth, differentiation and function.
Volume 1 provides. Trophoblast stem cells that differentiate into the mature trophoblast subtypes have been isolated in many species. In humans, we lack these cell-based tools. Accordingly, we carried out a systematic search to locate these cells within the placenta and used this information to devise a procedure for isolating them.
trophoblast [trof´o-blast] the peripheral cells of the blastocyst, which attach the zygote (fertilized ovum) to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism.
The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast. trophoblast (trof'ō-blast, trō'fō. from book Pathology of the Human Placenta Histologic sections revealed malignant villous trophoblast in eight microscopic fields within the placental infarct.
The pages and media below are UNSW Embryology content that relates to trophoblast development. Pages in category ‘Trophoblast’ The following 19 pages are in. The cells of the trophoblast have many unique qualities, and exhibit great variability across different species.
It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo. These aspects are all fully covered as well as studies on why it is not rejected by the mother as 'foreign' : Hardcover.
Learn more about Trophoblastic Neoplasms from related diseases, pathways, genes and PTMs with the Novus Bioinformatics Tool. The trophoblast compartment of the placenta comprises various subpopulations with distinct functions. They interact among each other by secreted signals thus forming autocrine or paracrine regulatory loops.
We established a first trimester trophoblast cell line (ACH-3P) by fusion of primary human first trimester trophoblasts (week 12 of gestation) with a human Cited by: Metastasizing trophoblast cells are also responsible for mediating implantation of the embryo into the endometrium.
Description Human trophoblast neoplasms PDF
Thus, trophoblast stem cells are used to model trophoectoderm differentiation and placental development in vitro. Research suggests that cultured trophoblast stem cells are dependent on FGF-4 signaling pathways.Pathology of the Human Placenta remains the most comprehensive and authoritative text in the field.
It provides extensive information on the normal placenta, encompassing physiology, metabolism, and endocrinology, and covers placental diseases in great detail. trophoblastic neoplasms, benign tumors, and multiple pregnancies.
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